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A new study just published on Feb 2011 in the journal of cancer makes a strong argument for applying hyperbaric oxygenation therapy (HBOT) for those patients who have had either surgery or radiation therapy for brain tumors. The study followed patients who had been treated with HBOT and there was a marked improvement in cognitive [...]

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Hyperbaric Oxygen Treats A Variety of Conditions

Monday, August 18th, 2008

Hyperbaric treatments said to cure, help treat a myriad of ills

08-03-2007 06:07; by Rebecca L. Sandlin

Mark Merrell was at his wits’ end. His young daughter, Maddie, was diagnosed as profoundly autistic. “We tried a number of therapies and been to a number of different places, and my kid’s pretty sick, and you accept that, and there’s just nothing anybody can do for her,” Merrell explained. “So we basically had to become our own advocates.” After investigating alternative therapies for his child, Merrell wound up in Florida, where he learned that hyperbaric medicine is being used to treat autism. “Many people like myself who are all right here in this Fishers-Carmel-Zionsville area, many of our doctors are not in Indiana,” he said. “Our backs are against the wall. We need help, and we can’t wait another six months for this study or another year for that drug. We need help now.” After using the hyperbaric chamber about 4 to 5 days per week, Merrell said the results of the treatments on Maddie have been astounding. “We can go out in public with our daughter now and nobody notices us … nobody looks at us. The change has been amazing,” he said. Merrell believes in the treatments so much he not only installed a hyperbaric chamber in his home, but also left his job as a police officer to open Oxyspa, a salon located at 11559 Cumberland Road in Fishers that features hyperbaric oxygen treatments. Oxsyspa is one a few locations in the Midwest that offers the treatments, using an FDA-approved hyperbaric chamber. When hyperbaric chambers were first installed in some Indianapolis-area hospitals, they were mainly used for treating burn victims or those who had carbon monoxide poisoning. Hospital chambers use a much greater pressure than what can be found at Oxyspa, but Merrell said the lighter pressure, non-invasive and non-pharmaceutical treatments are beginning to come into their own as an alternative therapy. David Darbro, M.D., the medical director who provides medical oversight at Oxyspa, became a believer in hyperbaric treatments after he changed roles and became a patient when he suffered a stroke three years ago. The stroke affected his speech. “You would not have been able to have understood me, were we speaking three years ago,” he said. Darbro drew a picture of a hyperbaric chamber to get his wishes across. After undergoing the pressurized oxygen treatments, he no longer takes medications and has no difficulty communicating. It just made sense, that when you check people’s oxygen, especially with chronic degenerative disorders, they seem to be low on oxygen and didn’t have any energy,” he said. Darbro said mild hyperbaric therapy is indicated in treatments of several illnesses and conditions, including migraine, heart problems and diabetes. It is also used to treat wounds, sports injuries, osteomyelitis, skin grafts, traumatic brain injury, cerebral palsy and multiple sclerosis. Darbro, who specializes in holistic medicine, said the treatments benefit the patient by helping to increase the body’s ability to absorb oxygen. “Your breathing is the key to opening the door to energy,” he said. “The idea of pressurized oxygen – putting oxygen under pressure – is the key, because it’s putting more oxygen in the fluid – the plasma – in between the red blood cells.” There are only 13 FDA-approved uses of hyperbaric treatments, so insurance may not cover treatments for other medical conditions. Articles of studies and other findings about the treatments have appeared in the Journal of American Medical Association. One article, published in 1990, calls hyperbaric treatments a controversial therapy. Another article, published in 2004, suggests hyperbaric oxygen therapy improves survival and limb salvage of patients with necrotizing soft tissue infections. A session at Oxyspa costs $80 for a treatment lasting around an hour, with packages available. A doctor’s prescription or order is mandatory before a client can begin therapy. Merrell said physicians from several disciplines including neurologists have referred their patients to the spa for treatments. He added the spa also follows FDA regulations by charting each client’s progress and condition during treatment. Cindy Beuoy, of Indianapolis, has been using the chamber since February and has noticed some benefits from regular visits. “I try to stay as healthy as I can. I’m a real pro-active person on health,” she said. “I found that, using the chamber, it helps me to sleep better. I exercise – I do strength training exercise three times a week and it helps my muscles recover faster from the exercise. I just feel my overall vitality is greater.”

Hyperbaric Oxygen Shows Promise for Migraine Sufferers

Thursday, July 24th, 2008

Oxygen therapies may ease headache pain

Jul 24, 2008 by Amy Norton

NEW YORK (Reuters Health) – Two forms of oxygen therapy may help manage two types of debilitating headache pain, a new research review suggests. In a review of nine small clinical trials, the researchers found that hyperbaric oxygen therapy showed promise for halting pain during migraine attacks. A similar treatment — normobaric, or normal-pressure, oxygen therapy — eased pain in people suffering from cluster headaches. The findings are published in the Cochrane Library, a publication of the Cochrane Collaboration, an international organization that evaluates medical research. Both migraines and cluster headaches can be debilitating. Migraines typically cause throbbing pain in one area of the head, often accompanied by nausea, vomiting or sensitivity to light and sound. Cluster headaches cause sharp pain on one side of the head, including the eye; that lasts anywhere from 15 minutes to a few hours and come in waves — repeated attacks over a few weeks to months, followed by a period of no symptoms. Hyperbaric oxygen therapy involves breathing pure oxygen in a sealed, pressurized chamber. With normobaric oxygen therapy, patients breathe pure oxygen from a portable unit under normal conditions. Normal-pressure oxygen has long been used for severe headache pain, and there is some evidence that hyperbaric oxygen could be helpful, but few controlled clinical trials have evaluated the therapies. For the current study, researchers were able to find nine clinical trials performed between 1981 and 2004 involving a total of 201 patients. When they combined data from three, they found that hyperbaric oxygen therapy was six times more likely to relieve migraine pain than a “sham” (placebo) therapy used for comparison. Similarly, one study showed that normal-pressure oxygen outperformed sham therapy in easing cluster headache pain. Another trial found the therapy to be effective, but not better than the medication ergotamine. None of the two forms of oxygen therapy prevented future headache attacks, however, lead researcher Dr. Michael H. Bennett, of Prince of Wales Hospital in Randwick, Australia, told Reuters Health. He said that based on the evidence, people with cluster headaches who are not finding quick or complete relief from their medication could ask their doctor about normobaric oxygen therapy. Hyperbaric oxygen could be an option for stubborn migraine pain, according to Bennett, but it may not be all that practical. “Unfortunately, this treatment will be relatively expensive and may not be covered by medical insurance or provided by local medical services,” he said. “It is likely that hyperbaric oxygen will only be used in the very worst cases where relief is not obtained by any alternative method.” Exactly why oxygen therapy works is not entirely clear. Bennett noted that migraines involve blood vessel dilation in the head, and hyperbaric oxygen causes vessels to constrict, which may help explain the pain reduction. There is also evidence that hyperbaric oxygen blocks the “chemical pathways” that lead people to feel migraine pain, he explained. As for cluster headaches, they are associated with altered activity in certain brain areas. “In general,” Bennett explained, “oxygen seems to return the activity of these areas to normal, and may be directly responsible for the effect of oxygen on the headache.” SOURCE: Cochrane Library, online July 16, 2008.

Study–Hyperbaric Oxygen for Migraines & Cluster Headaches

Wednesday, July 16th, 2008

Normobaric and hyperbaric oxygen therapy for migraine and cluster headache.

Cochrane Database Syst Rev. 2008 Jul

Bennett MH, French C, Schnabel A, Wasiak J, Kranke P.

Diving and Hyperbaric Medicine, Prince of Wales Hospital, Barker Street, Randwick, NSW, Australia, 2031.

BACKGROUND: Migraine and cluster headaches are severe and disabling. Migraine affects up to 18% of women, while cluster headaches are much less common (0.2% of the population). A number of acute and prophylactic therapies are available. Hyperbaric oxygen therapy (HBOT) is the therapeutic administration of 100% oxygen at environmental pressures greater than one atmosphere, while normobaric oxygen therapy (NBOT) is oxygen administered at one atmosphere. OBJECTIVES: To assess the safety and effectiveness of HBOT and NBOT for treating and preventing migraine and cluster headaches. SEARCH STRATEGY: We searched the following in May 2008: CENTRAL, MEDLINE, EMBASE, CINAHL, DORCTIHM and reference lists from relevant articles. Relevant journals were hand searched and researchers contacted. SELECTION CRITERIA: Randomised trials comparing HBOT or NBOT with one another, other active therapies, placebo (sham) interventions or no treatment in patients with migraine or cluster headache. DATA COLLECTION AND ANALYSIS: Three reviewers independently evaluated study quality and extracted data. MAIN RESULTS: Nine small trials involving 201 participants were included. Five trials compared HBOT versus sham therapy for acute migraine, two compared HBOT to sham therapy for cluster headache and two evaluated NBOT for cluster headache.Pooling of data from three trials suggested that HBOT was effective in relieving migraine headaches compared to sham therapy (relative risk (RR) 5.97, 95% confidence interval (CI) 1.46 to 24.38, P = 0.01). There was no evidence that HBOT could prevent migraine episodes, reduce the incidence of nausea and vomiting or reduce the requirement for rescue medication. There was a trend to better outcome in a single trial evaluating HBOT for the termination of cluster headache (RR 11.38, 95% CI 0.77 to 167.85, P = 0.08), but this trial had low power.NBOT was effective in terminating cluster headache compared to sham in a single small study (RR 7.88, 95% CI 1.13 to 54.66, P = 0.04), but not superior to ergotamine administration in another small trial (RR 1.17, 95% CI 0.94 to 1.46, P = 0.16). Seventy-six per cent of patients responded to NBOT in these two trials.No serious adverse effects of HBOT or NBOT were reported. AUTHORS’ CONCLUSIONS: There was some evidence that HBOT was effective for the termination of acute migraine in an unselected population, and weak evidence that NBOT was similarly effective in cluster headache. Given the cost and poor availability of HBOT, more research should be done on patients unresponsive to standard therapy. NBOT is cheap, safe and easy to apply, so will probably continue to be used despite the limited evidence in this review.